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Almost 6 women in 10 (60 percent) of all women have at least one distinctly painful bladder infection during their lifetimes. Unfortunately, nearly 20 percent of women who have a bladder infection will have another. Also, 30 percent of that group will have yet another bout.
Of the last group of women, 80 percent will have bladder infection recurrences. They are most common in the age groups 25-29 and over 55 years. For example, in the United Kingdom alone, it is estimated that 1 woman in 3 will have a UTI before the age of 24. And that half of all women will have at least one UTI during their lifetime. It is a worldwide problem, says professor Chris Thomas, an expert in bacteria at the University of Birmingham.
There are many types of urinary tract infection depending on the part affected: the kidneys (nephritis), the ureters (ureteritis), the bladder (cystitis), or the urethra (urethritis). The urinary tract produces, stores, and eliminate urine – a combination of water and waste products that passes out of the body as fluid.
*Based on various available sources and studies, our research and practical experience. Last modified on November 13, 2019.
Because the urinary system is structured in a way that helps ward off pathogenic bacteria, an infection does not always occur when they are introduced into the bladder. Also, the urinary tract consists of a number of natural safeguards that protect it against infection-causing bacteria. This natural self-defense system includes:
Normally, urine is normally sterile, that is, free of bacteria, viruses, and fungi. So, it functions as an antiseptic, helping to wash potentially harmful bacteria out of the body during normal urination.
Urine contains large quantities of urea. It is the colorless, crystalline end product manufactured within the liver and excreted from the body via urinary tract. Known for its antiseptic and bactericidal properties, urea helps to inhibit the growth of many types of detrimental bacteria, including Eschericia coli (E. coli)and Staphylococcus.
These tubes carry urine from the kidneys to the bladder. The ureters and the bladder are structurally designed to prevent urine from backing up toward the kidneys.
When bacteria infect the bladder, the cells that line the bladder, literally, sacrifice themselves and self-destruct (a process called apoptosis). In so doing, they fall away from the lining, carrying the bacteria with them. This process, suggested by some interesting research, eliminates about 90 percent of the E. coli.
In fact, the immune defenses continuously fight bacteria and other harmful micro-invaders. In addition, antibacterial substances in the mucous lining of the bladder eliminate many organisms.
In healthy fertile women, vagina is colonized with by lactobacilli, beneficial micro-organisms that maintain a highly acidic environment (low pH). They play an important role in protecting the host from urogenital infections. Lactobacilli also produce hydrogen peroxide, which helps to eliminate pathogenic bacteria and reduces the ability of E. coli to adhere to vaginal cells.
Our body is constantly challenged by all kinds of bacteria, both commensal (as a part of our normal flora*) and pathogenic (infectious). At the same time, antimicrobial molecules (peptides), constantly secreted by our innate immune system, protect the body from bacterial overgrowth, keeping in balance our microbiota – all micro-organisms and viruses coexisting in the gastrointestinal tract.
These antimicrobial peptides, called defensins, act mainly by disrupting the structure of pathogenic bacterial cell membranes. It is a very complex and sophisticated defense mechanism.
One of the most prominent antimicrobial molecules is the human beta defensin 1 (hBD1). It is constantly expressed by epithelial cells and exhibits complex and diverse host antimicrobial strategies. Besides disrupting the bacterial cell walls, it creates a net-like structure surrounding and entrapping infectious bacteria.
*Our normal flora contains approximately one hundred trillion bacteria covering our body and living in the gastrointestinal tract.
In most cases, about 80 percent in adults, urinary tract infection is caused by a variety of pathogens (infectious bacteria) normally present in the intestines, especially in the rectum. Nearly all infections of the lower urinary tract and bladder are caused by a few strains of E. coli bacteria, called uropathogenic Escherichia coli (UPEC).
The only way to diagnose an infection is checking a urine sample.
Urinary Analysis (U/A)
This test is commonly performed in the doctor’s office or in lab. It just takes a few minutes – a dipstick is placed in the urine sample and up to ten different substances can be detected.
Microscopic Urinalysis (U/A micro)
A doctor may also wait a few hours for the lab to run a microscopic urinalysis – a drop of urine is examined under a microscope – to help in the decision whether or not to start an antibiotic treatment while the urine culture is running.
With no doubt, urine culture is the most accurate test to determine for sure whether or not an infection is present. The lab puts the urine sample in an incubator. If any bacteria are in the sample, they will multiply and show up. However, it takes 24 to 48 hours for the bacteria to grow enough to be detected.
Antibiotic Susceptibility Testing (AST)
If only one type of bacteria grows in the culture, the lab will expose the bacteria to a variety of antibiotics to see to which ones the bacteria are sensitive. This usually takes one day after the culture is positive. It helps to decide which antibiotic is best for the infection.
In most cases, in about 80 percent of adult women, urinary tract infections are caused by a variety of infectious bacteria (uropathogens) normally present in the intestinal tract, especially in the rectum.
Nearly all infections of the lower urinary tract and bladder are sue to a few strains of E. coli bacteria, called uropathogenic Escherichia coli (UPEC).
Below there are the common risk factors – attributes, characteristics or exposures – that increase your likelihood of developing a urinary tract infection:
The tips for UTI prevention may be summarized as follows:
In the United States alone, more than 11 million women each year are given antibiotics for urinary tract infections. Typically, those who have frequent recurrences (three or more UTIs a year) are offered:
Usually, stronger antibiotics are given for single, acute episodes of bladder infection (cystitis). After acute symptoms have subsided, prophylactic, or preventive, therapy with low-dose antibiotics is recommended.
Besides antibiotics, medical treatments also include:
These treatments are normally employed in a trial-and-error fashion with varying degrees of success.
In fact, antibiotic treatments do not successfully kill all the bacteria participating in the infection. And they may encourage many of the bacteria to persist in a resting state.
Therefore, current standard drug treatments for bladder infections are still not adequate. This phenomenon may account for many of the stubborn, repeated urinary tract infections.
Although routinely used, antibiotic treatments have many drawbacks. Here’re the most common ones:
Also, all antibiotic therapies carry with them the risks of developing:
Therefore, due to all these hazards, especially of prolonged antibiotic therapy, the use of antibiotics should be reduced to the absolute minimum. Women who take antibiotics over a long period of time are at increased risk of heart attack or stroke, according to research carried out in nearly 36,500 women. In addition, a study published in 2017 found the antibiotics may raise the risk of bowel cancer.
One possible factor behind recurrent urinary tract infection may be the ability of bacteria to attach to cells lining the urinary tract. The symptoms sometimes can be caused by chemical irritation such as bath additives or soaps. They may disappear, if toiletries are changed.
Also, you are likely to continue having urinary tract infections, if you have had three or more a year. In other words, you can expect to get another infection within 18 months of the last one, or even more frequently.
Usually, the latest infection stems from a strain or type of bacteria that is different from the infection before it, indicating a separate infection. Even when several urinary tract infections in a row are due to E. coli, slight differences in the bacteria indicate distinct infections.
However, you may have recurrent symptoms suggestive of urinary tract infection – but without infection being present. This condition is not serious but can be troublesome.
Chronic or recurrent urinary tract infections should always be treated thoroughly because of the chance of a kidney infection (nephritis).
UTIs are the most common bacterial infections found in nursing home residents, accounting for:
The incidence of UTIs is higher in the elderly due to genitourinary abnormalities, urolithiasis (stones in the kidney, bladder, and/or urethra), dehydration, and diabetes, among other causes.
These are considered complicated UTIs – in the presence of factors that predispose to persistent or relapsing infection, such as:
UTIs are prone to recur when urinary tract abnormalities persist or treatment ineffectively eradicates resistant bacteria.
UTIs are considered recurrent when ≥ 3 occur within 1 year or ≥ 2 occur in a 6-month period. The anticipated recurrence rate of complicated UTIs at 4 to 6 weeks following completion of therapy is 40% to 60%.
Current practice standards recommend not treating asymptomatic UTIs to avoid contributing to bacterial antibiotic resistance.
The frequent use of antibiotics, such as quinolones, which are increasingly inactive against these organisms, contributes to the overgrowth of bacteria in the gastrointestinal tract and their appearance in the genitourinary tract.
As UTI-causing bacteria become more resistant to available antibiotics, the need to explore new strategies for managing UTIs is clear.
Contrary to a popular belief and common medical practice, people with urinary tract infection do not have to suffer and be exposed to countless rounds of vicious antibiotics.
With the help of antibacterial and anti-inflammatory herbs, nutrients and phytonutrients, it is possible to get through both acute and chronic UTI by:
Compared to standard medical treatments (read: antibiotics), the natural, non-pharmacological approach to UTI infection is clearly a superior option – much safer and without side effects.
It is our working experience that bladder infection can be successfully controlled and most importantly prevented with the help of natural formulations. Therefore, you, or someone you know or hold dear, who suffers from urinary tract infection should give this approach serious consideration.
I have been plagued with bladder infections for about 3 years now. Having a bladder infection every 6 – 8 weeks was very unacceptable to me. Ending up in emergency in the middle of the night in excruciating pain, blood in my urine and fever was not much fun. The treatment every time was a round of antibiotics.
I started doing my own research and came upon Uribiotic. I ordered two bottles and waited for the next infection which didn’t let me down. Instead of the antibiotics (which I made sure I always had on hand), I started on the Uribiotic as per the instructions.
Within 8 hours the pain was gone and I was comfortable. I stayed on the Uribiotic for the complete round as recommended and now take one three times a day.
I have been infection-free for 2 months and want to keep it that way.
I highly recommend this product. In my mind, anytime I can avoid antibiotics it is a good thing!
British Columbia, Canada
I have an elderly female nursing home patient who has chronic recurrent UTIs and multiple drug allergies.
The Uribiotic Formula has been very helpful to make the frequency of her infections much less often.
For years I have been plagued with UTIs. Each time trying to fight it off with baking soda, Alka-Seltzer, drinking lots of water and searching the web for natural remedies, only to end up at the dreaded Urgent Care to get antibiotics. Some of them even gave me bad side effects.
I found Uribiotic Formula on my last web search and I read some of the testimonials and thought I would give it a try.
I was amazed! It really, really worked. I didn’t go on antibiotics and my infection was cured.
Thank you a million times over! What a freedom to be able to have a natural cure and not have to be on antibiotics…
Uribiotic really works and I would highly recommend it to anyone who suffers from a UTI.
Wheelersburg, Ohio, USA
I would like to share my experience with Uribiotic Formula. It is my belief that I contracted a community-based exposure to bacteria that would later come to haunt me for years. While at a stay in the hospital delivering my daughter, the nurse failed to realize that she had not tended to my catheter, which I had due to being induced and receiving an epidural. In short, I left the hospital with a UTI and had recurring UTIs for years since then, even having to be placed on intravenous antibiotics at one point.
My primary care providers along the way failed to treat me as well, instead resigning care to prescribing antibiotics monthly for the last two years straight. I knew this could not be good for me. So I was determined to find a better way to regain my health.
As I was researching the subject I came across your website. And I knew instantly just by the details on the site that the producers of the product and site were well versed on the subject. I knew that I could trust what I was reading since I had done my own research as well, so I knew what to look for in terms of potential causes of UTIs.
On the first day of taking the Uribiotic, I could tell that something was occurring. I was still not sure, if it would be a cure given my long history of UTIs. So to be sure, I took the advice offered on the site and went through three bottles of Uribiotic Formula. Additionally, I also began taking the oregano and UT ProbioticsUltra as well.
I can honestly say that I am now symptoms-free, my health is back. And for the first time in years, I have my life back! I am no longer at the mercy of a practitioner that was unable to effectively treat me. I feel healthy and free!
Thank you so much for this amazing product!
Murrieta, California, USA
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